Right-click in the Hyperview browser, and select the Make This Topic My Content Pane Home Page (if content pane has focus) or Make This Topic My Index Pane Home Page (if index pane has focus) menu option.
This allows you to set your "home page" (where the Home button takes you) for either the content pane or the index pane to the document that has focus in the browser.
You can configure Hyperview to show the home pages you have selected on startup.